MEWDS (Multiple Evanescent White Dot Syndrome)

• A rare, unilateral, self-limiting inflammatory disease
• Afflicts young women more than men in a 4:1 ratio.
• Patients typically present complaining of
  • Sudden, painless, monocular decline in central acuity
  • Photopsias-- def. appearance as of sparks or flashes in retinal irritation
  • Dyschromatopsia-- def> disorder of color vision
  • Central/paracentral scotomas
• Visual acuity usually in the  20/40-20/400
• Fluorescein angiography of active lesions typically demonstrate a "wreath-like" hyperfluorescence of the white dots
• Disease is usually self limited (resolves in weeks to months) with an excellent prognosis.
• There are no known treatment options.

References

Multiple Evanescent White Dot Syndrome (MEWDS): 24 y.o. woman with one week duration of central scotoma, OD.
Presented by Sudeep Pramanik, MD, MBA, Hilary A. Beaver, MD http://webeye.ophth.uiowa.edu/eyeforum/cases/37-MultipleEvanescentWhiteDotSyndromeMEWDS.htm