Currently Approved LMWHs for the Treatment of Acute PE:

• Enoxaparin-1 mg/kg every 12 hours subcut
• Tinzaparin 175 Units/kg once daily subcut
• The pentasaccharide: Fondaparinux- at a dose of 5 mg for body weight <50 kg, 7.5 mg for 50-100 kg, and 10 mg for >100 kg, once daily

Make sure to monitor platelet counts regardless of agent chosen.

 

 

References

Konstantinides. Acute pulmonary embolism revisited. Heart. June 2008