The Infectious Disease Society of America in 2023 recommended a single dose of an aminoglycoside for uncomplicated cystitis treatment in those with resistance or other contraindications to first line oral agents who were otherwise well enough to be discharged. This very small study (13 participants) suggest this strategy works for complicated (“male sex, urinary flow obstruction, renal failure or transplantation, urinary retention, or indwelling catheters”) cystitis patients who could otherwise be discharged home.

References

Academic Emergency MedicineVolume 31, Issue 7 p. 649-655

Prospective evaluation of single-dose aminoglycosides for treatment of complicated cystitis in the emergency department

Jordan E. Jenrette PharmD, Kyle Coronato PharmD, Matthew A. Miller PharmD, Kyle C. Molina PharmD, Alexander Quinones MD, Gabrielle Jacknin PharmD

First published: 07 March 2024

https://doi.org/10.1111/acem.14886