• AKI can be seen in up to 40% of ICU patients
• Around 5-10% require treatment with renal replacement therapies
• The most common cause is acute tubular necrosis
• Definition by KDIGO:

1. Increase in Creatinine by 0.3 or more within 48 hours OR
2. Increase in Cr to >1.5 x baseline, presumed to have occured within the prior 7 days
3. Urine volume <0.5 mL/kg/hr x 6 hours

References

KDIGO Clinical Practice Guidelines, 2012.