• Invasive candidal infections can carry a high mortality (up to 40%) and can hard to diagnose
• In the ICU it is important to know which patients are at risk for developing invasive candidal infections

Risk factors for invasive candidal infections

• Critical illness (long ICU stays)
• Abdominal surgery (anastomotic leaks, repeat laporatomies)
• Necrotizing pancreatitis
• Hematologic malignencies
• Solid organ transplant
• Solid organ tumors
• Neonates (low birth wt, preterm)
• Use of broad spectrum antibiotics
• Central lines/PICC lines
• TPN
• Hemodialysis
• Steroid use
• Candidal colinization (urine, sputum)  

References

Invasive Candidiasis

Bart Jan Kullberg, M.D., Ph.D., and Maiken C. Arendrup, M.D., Ph.D.

N Engl J Med 2015; 373:1445-1456October 8, 2015DOI: 10.1056/NEJMra1315399